کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6225167 1607503 2010 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Neurodevelopment in Children with Hypoplastic Left Heart Syndrome
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Neurodevelopment in Children with Hypoplastic Left Heart Syndrome
چکیده انگلیسی

ObjectiveTo assess neurodevelopment in children with hypoplastic left heart syndrome (HLHS) or other types of functionally single ventricle (univentricular heart, UVH) and to estimate the effect of possible clinical predictors on outcome.Study designA total of 22 patients with HLHS and 14 with UVH, surviving after palliative surgery performed in the same center, and 42 healthy control subjects were examined at a median age of 30.2 months neurologically and according to the Bayley Scales of Infant Development in a population based prospective neurodevelopmental follow-up study.ResultsThe mean Mental Developmental Index was significantly lower (89.9) in patients with HLHS than in control subjects (105.5, P < .001), whereas there was no difference between patients with UVH (98.5) and control subjects. The mean Psychomotor Developmental Index in patients with HLHS (80.7, P < .001) as well as in those with UVH (94.5, P = .016) was significantly inferior to that in control subjects (105.3).ConclusionsIn patients with HLHS, mean Mental Developmental Index lags behind control subjects. Psychomotor Developmental Index is impaired in patients with both HLHS and UVH. Routine neurodevelopmental follow-up is recommended for this seriously ill patient group.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Pediatrics - Volume 157, Issue 3, September 2010, Pages 414-420.e4
نویسندگان
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