کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6240465 1280424 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluation of mold exposure in cystic fibrosis patients' dwellings and allergic bronchopulmonary risk
ترجمه فارسی عنوان
ارزیابی قرار گرفتن در معرض قالب در خانه های بیماران فیبروز کیستیک و خطر برونکوپلاستی آلرژیک
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
چکیده انگلیسی

Very few studies have been conducted on cystic fibrosis (CF) patients' exposure to the indoor environment and, to our knowledge, there are no studies dealing with the link between specific fungal environmental exposure at home and fungal colonization resulting in allergic bronchopulmonary aspergillosis (ABPA). Fungal exposure of CF adult patients with ABPA (n = 4) with fungal sensitization (n = 7) and with no ABPA (n = 5) was assessed in 16 homes by dust sampling with electrostatic dust fall collectors (EDCs). Aspergillus fumigatus was specifically quantified by real-time quantitative polymerase chain reactions (qPCRs), and A. fumigatus DNA concentrations were significantly higher in homes of ABPA patients (p < 0.001). Results indicate that indoor fungal contamination could be a factor favoring ABPA and suggest that environmental surveys could help in preventing fungal risk in CF patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cystic Fibrosis - Volume 14, Issue 2, March 2015, Pages 242-247
نویسندگان
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