Pulse wave amplitude reduction: A surrogate marker of micro-arousals associated with respiratory events occurring under non-invasive ventilation?

PWA reduction is a sensitive marker with a high PPV for the detection of EEG-MA associated with respiratory events during NREM sleep in stable OHS patients treated by NIV. In this situation, PWA could be used to improve scoring of hypopneas and allow an appropriate assessment of sleep fragmentation related to respiratory events.