کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6242140 1280575 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewDefining hyperinflation as 'dynamic': Moving toward the slope
ترجمه فارسی عنوان
بررسی تعرفه تورم به عنوان "پویایی": حرکت به سمت شیب
کلمات کلیدی
اثر برونکودیلاتور، ورزش، هلیم، هیپوکسیا، بیماری های ریوی، انسدادگر اندازه گیری حجم ریه،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
چکیده انگلیسی

SummaryMeasuring the severity of dynamic hyperinflation is a useful clinical approach to assess the effect of therapeutic interventions and explain their impact on exercise tolerance. Dynamic hyperinflation is typically quantified by the change in end expiratory lung volume from rest to the end of exercise. The result may be inconsistent with disease severity and does not clearly explain how exercise tolerance improves with therapy. Using a re-examination of selected studies, we suggest an operational definition of dynamic hyperinflation using the slope derived from serial measures of inspiratory capacity expressed as a linear function of ventilation that clearly differentiates whether therapies affect static or dynamic hyperinflation or affect lung volume only as a consequence of reducing ventilation. With this approach, the magnitude of the result is consistent with disease severity and is a more reliable outcome as it uses serial measures rather than a single time point estimate. The therapies re-evaluated are breathing helium or hyperoxic gas mixtures, bronchodilation and exercise training. A clear definition of dynamic hyperinflation will assist clinicians in assessing the impact of therapeutic interventions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Medicine - Volume 107, Issue 7, July 2013, Pages 953-958
نویسندگان
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