کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6257229 | 1612947 | 2015 | 7 صفحه PDF | دانلود رایگان |
- The use of recognition memory tasks in neuroendocrine research is reviewed.
- Advantages of recognition tasks as compared to other memory tasks are discussed.
- Gonadal hormones enhance while adrenal hormones impair memory.
- Increases in dendritic spine density may contribute to enhancements of memory.
The recognition memory tasks, novel object and novel object location, have been beneficial to neuroendocrine research concerning the effects of gonadal and adrenal hormones on cognitive function. This review discusses the advantages of these tasks in comparison with other learning and memory tasks. Experiments conducted across a number of laboratories show that gonadal hormones, both estradiol and testosterone, promote memory while the adrenal hormone, corticosterone, impairs memory. The effects of these steroid hormones on spine density in the prefrontal cortex and hippocampus are also briefly presented. Overall, results show that these steroid hormones are potent modulators of memory consolidation in rodent models.
Journal: Behavioural Brain Research - Volume 285, 15 May 2015, Pages 158-164