کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6257340 1612953 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Research reportTasting calories differentially affects brain activation during hunger and satiety
ترجمه فارسی عنوان
گزارش تحقیقات کالیبراسیون های مختلف بر فعال شدن مغز در طی گرسنگی و سیری تاثیر می گذارد
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی


- An important function of eating is ingesting energy.
- We found no evidence for energy sensing in the oral cavity in general.
- Energy sensing was modulated by hunger state in several brain regions.
- Energy sensing is a hunger state dependent process.

An important function of eating is ingesting energy. Our objectives were to assess whether oral exposure to caloric and non-caloric stimuli elicits discriminable responses in the brain and to determine in how far these responses are modulated by hunger state and sweetness. Thirty women tasted three stimuli in two motivational states (hunger and satiety) while their brain responses were measured using functional magnetic resonance imaging in a randomized crossover design. Stimuli were solutions of sucralose (sweet, no energy), maltodextrin (non-sweet, energy) and sucralose + maltodextrin (sweet, energy). We found no main effect of energy content and no interaction between energy content and sweetness. However, there was an interaction between hunger state and energy content in the median cingulate (bilaterally), ventrolateral prefrontal cortex, anterior insula and thalamus. This indicates that the anterior insula and thalamus, areas in which hunger state and taste of a stimulus are integrated, also integrate hunger state with caloric content of a taste stimulus. Furthermore, in the median cingulate and ventrolateral prefrontal cortex, tasting energy resulted in more activation during satiety compared to hunger. This finding indicates that these areas, which are known to be involved in processes that require approach and avoidance, are also involved in guiding ingestive behavior. In conclusion, our results suggest that energy sensing is a hunger state dependent process, in which the median cingulate, ventrolateral prefrontal cortex, anterior insula and thalamus play a central role by integrating hunger state with stimulus relevance.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Behavioural Brain Research - Volume 279, 15 February 2015, Pages 139-147
نویسندگان
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