کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6261770 | 1613247 | 2014 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Research reportc-Fos positive nucleus reveals that contextual specificity of latent inhibition is dependent of insular cortex Research reportc-Fos positive nucleus reveals that contextual specificity of latent inhibition is dependent of insular cortex](/preview/png/6261770.png)
- Insular cortex is involved in taste processing.
- Contextual shift affects to insular cortex activity when a taste is used.
- Contextual specificity of latent inhibition shows this phenomenon.
- Immunopositive cells indicate different processing of a same taste under shift context.
The present study analyzed the functional activity of granular and agranular insular cortices in contextual specificity of latent inhibition using a conditioned taste aversion paradigm. c-Fos immunolabeling was examined in insular cortex in preexposed and no preexposed groups under similar and different context conditions. Result showed that the exposition to a novel taste increased c-fos activity in insular cortex. However, a context shift caused an increase in immunolabeling in animals preexposed to saccharine. These results suggest insular cortex is part of a complex system to evaluate taste-response, and it may read the meaning of taste stimuli depending on the context.
Journal: Brain Research Bulletin - Volume 108, September 2014, Pages 74-79