کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6266091 1614508 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The complexity of small circuits: the stomatogastric nervous system
ترجمه فارسی عنوان
پیچیدگی مدارهای کوچک: سیستم عصبی دندانپزشکی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
چکیده انگلیسی


- Analysis of small circuits reveals interacting dynamics at different time scales.
- Synaptic and intrinsic properties, neuromodulation, and long-term regulation interact.
- Neuromodulation ties together short-term flexibility and long-term stability.
- Circuit parameters are variable, but correlated to ensure stable function.

The crustacean stomatogastric nervous system is a long-standing test bed for studies of circuit dynamics and neuromodulation. We give a brief update on the most recent work on this system, with an emphasis on the broader implications for understanding neural circuits. In particular, we focus on new findings underlining that different levels of dynamics taking place at different time scales all interact in multiple ways. Dynamics due to synaptic and intrinsic neuronal properties, neuromodulation, and long-term gene expression-dependent regulation are not independent, but influence each other. Extensive research on the stomatogastric system shows that these dynamic interactions convey robustness to circuit operation, while facilitating the flexibility of producing multiple circuit outputs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Neurobiology - Volume 41, December 2016, Pages 1-7
نویسندگان
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