کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6266202 | 1614518 | 2015 | 6 صفحه PDF | دانلود رایگان |
- Theta-gamma coupling supports memory processes in the entorhinal-hippocampal network.
- Theta-modulated slow gamma may promote memory retrieval.
- Theta-modulated fast gamma may facilitate memory encoding.
- Theta-nested gamma reflects gamma rhythmic inhibition and theta rhythmic excitation.
For decades, theta rhythms (â¼5-10Â Hz) have been thought to play a critical role in memory processing in the entorhinal-hippocampal network. However, recent evidence suggests that successful memory performance also requires coupling of â¼30-100Â Hz gamma rhythms to particular phases of the theta cycle. Recent insights imply ways in which theta-gamma coupling may facilitate transfer of information throughout the entorhinal-hippocampal network. Activating gamma-modulated cell assemblies at a particular theta phase may allow the network to produce a more powerful output by ensuring that distributed cells fire closely in time. I hypothesize that such a mechanism would serve to facilitate either memory encoding or memory retrieval, depending on which type of gamma rhythms are recruited.
Journal: Current Opinion in Neurobiology - Volume 31, April 2015, Pages 45-50