Characterization of a rat hypoxia-ischemia model where duration of hypoxia is determined by seizure activity

► Gives an improved version of a hypoxia-ischemia model for testing neuroprotectants. ► Establishes the relationship between clonic tonic seizures during hypoxia and infarct induction in the brain. ► Establishes the relationship between infarct induction at days 3 and 15 post HI in conventional and modified HI model.