کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6272817 1614793 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewGlycemic control after brain injury: Boon and bane for the brain
ترجمه فارسی عنوان
نظارت بر کنترل گلیسمی پس از آسیب مغزی: فحش و ناسزا برای مغز
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
چکیده انگلیسی


- Hyperglycemia is common in patients with BI.
- Intensive glucose-lowering therapy results in an increased rate of hypoglycemia.
- The acutely injured brain is prone to energetic undersupply.
- Careful insulin application without an adherence to strict euglycemia seems beneficial for the injured brain.

Hyperglycemia is a common phenomenon in the early phase of brain injury (BI). The management of blood glucose levels after BI, however, is subject of a growing debate. The occurrence of elevated blood glucose concentrations is linked to increased mortality and worse neurologic outcomes indicating the necessity for therapeutic glucose-lowering. Intensive glucose-lowering therapy, on the other hand, inevitably results in an increased rate of hypoglycemic episodes with detrimental effects on the injured brain. In this review, we give an overview on the current knowledge about causes and pathophysiological consequences of dysglycemia in patients with BI and offer some suggestions for clinical glucose management.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 283, 26 December 2014, Pages 202-209
نویسندگان
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