Sensorimotor performance asymmetries predict hand selection

► We proposed that handedness is based on hemispheric differences in neural control. ► We examined if sensorimotor performance asymmetries give rise to active hand choices. ► We modulated sensorimotor performance asymmetries by occlusion of visual feedback. ► We found hand preference to change respectively to performance asymmetries. ► We concluded that sensorimotor performance asymmetries predict hand choice.