کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6275772 1614873 2012 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Characterization of oxaliplatin-induced chronic painful peripheral neuropathy in the rat and comparison with the neuropathy induced by paclitaxel
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Characterization of oxaliplatin-induced chronic painful peripheral neuropathy in the rat and comparison with the neuropathy induced by paclitaxel
چکیده انگلیسی
Oxaliplatin evokes a chronic painful peripheral sensory neuropathy in rat. ▶Oxaliplatin induces abnormal spontaneous discharge in A-fibers and C-fibers. ▶Oxaliplatin induces swelling and vacuolation in axonal mitochondria. ▶IENF degeneration is present without degeneration of peripheral nerve axons. ▶Oxaliplatin-induced effects are very similar to those induced by paclitaxel.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 203, 17 February 2012, Pages 194-206
نویسندگان
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