Expression of frontotemporal dementia with parkinsonism associated to chromosome 17 tau induces specific degeneration of the ventral dentate gyrus and depressive-like behavior in mice

▶Mice overexpressing mutated human tau show ventral dentate gyrus degeneration. ▶Mice overexpressing mutated human tau show adult neurogenesis alterations. ▶Mice overexpressing mutated human tau show depressive-like behavior.