Pancreatitis-associated protein-I and pancreatitis-associated protein-III expression in a rat model of kainic acid-induced seizure

▶Expressions of PAP-I (Reg2) and PAP-III after seizure were examined. ▶PAP-I and -III were expressed in hippocampus and parahippocampal area after seizure. ▶The expressions were observed at a maximal level 1 day after seizure. ▶The majority of positive neurons co-localized with c-Jun, but not with GAD. ▶The results may suggest that PAP inductions would protect neurons against seizure.