mRNA distribution of the thalidomide binding protein cereblon in adult mouse brain

▶ All brain neurons express cereblon mRNA with various intensities. ▶ Glial expression of cereblon mRNA is limited. ▶ Cereblon mRNA levels are the highest in hippocampal pyramidal cells and cerebellar Purkinje cells. ▶ Cereblon mRNA is enriched in serotonergic and noradrenergic neurons as well.