کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6286769 | 1299047 | 2012 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Nerve dependence in tissue, organ, and appendage regeneration
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Nerve dependence in tissue, organ, and appendage regeneration Nerve dependence in tissue, organ, and appendage regeneration](/preview/png/6286769.png)
چکیده انگلیسی
Many regeneration contexts require the presence of regenerating nerves as a transient component of the progenitor cell niche. Here we review nerve involvement in regeneration of various structures in vertebrates and invertebrates. Nerves are also implicated as persistent determinants in the niche of certain stem cells in mammals, as well as in Drosophila. We consider our present understanding of the cellular and molecular mechanisms underlying nerve dependence, including evidence of critical interactions with glia and non-neural cell types. The example of the salamander aneurogenic limb illustrates that developmental interactions between the limb bud and its innervation can be determinative for adult regeneration. These phenomena provide a different perspective on nerve cells to that based on chemical and electrical excitability.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Trends in Neurosciences - Volume 35, Issue 11, November 2012, Pages 691-699
Journal: Trends in Neurosciences - Volume 35, Issue 11, November 2012, Pages 691-699
نویسندگان
Anoop Kumar, Jeremy P. Brockes,