Diversity of Saccharomyces cerevisiae yeasts associated to spontaneously fermenting grapes from an Italian “heroic vine-growing area”

► We analyzed wild Saccharomyces cerevisiae yeasts from grapes of “heroic vineyards”. ► Use of different molecular techniques is necessary for reliable strain biotyping. ► Strain variability for metabolite production was tested in two grape musts. ► High metabolic biodiversity was found only in the isolation grape must fermentation. ► A heroic vineyards strain showed higher implantation than strain of different origin.