کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6370067 1623845 2015 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Population structure and the rate of evolution
ترجمه فارسی عنوان
ساختار جمعیت و نرخ تکامل
کلمات کلیدی
بخش تقسیم جمعیت، مهاجرت، انتخاب وابسته به محدوده رایت مدل فیشر، نزدیک شدن تقسیم،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
چکیده انگلیسی
The way population size, population structure (with migration), and spatially dependent selection (where there is no globally optimal allele), combine to affect the substitution rate is poorly understood. Here, we consider a two patch model where mutant alleles are beneficial in one patch and deleterious in the other patch. We assume that the spatial average of selection on mutant alleles is zero. We take each patch to maintain a finite number of N adults each generation, hence random genetic drift can independently occur in each patch. We show that the principal way the population size, N, when large, affects the substitution rate, R∞, is through its dependence on two composite parameters. These are the scaled migration rate M (∝ population size × migration rate), and the scaled selection intensity S (∝population size × beneficial effect of a mutant). Any relation between S and M that arises for ecological/evolutionary reasons can strongly influence the way the substitution rate, R∞, depends on the population size, N. In the simplest situation, both M and S are proportional to N, and this is shown to lead to R∞ increasing with N when S is not large. The behaviour, that R∞ increases with N, is not inevitable; a more complex relation between S and M can lead to the opposite or other behaviours. In particular, let us assume that dM/dN is positive, as would occur if the migration rate were constant, S is not large, and S depends on M (i.e., S=S(M)). We then find that if S(M) satisfies S(M)>((1+M)/1+2M)S(0) then the substitution rate, R∞, increases with N, but if S(M)<((1+M)/1+2M)S(0) then R∞ decreases with N.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 365, 21 January 2015, Pages 486-495
نویسندگان
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