کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6370762 1623873 2013 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Modelling of thrombus growth in flow with a DPD-PDE method
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
Modelling of thrombus growth in flow with a DPD-PDE method
چکیده انگلیسی
The model takes into account consecutive stages of clot growth. First, a platelet is weakly connected to the clot and after some time this connection becomes stronger due to other surface receptors involved in platelet adhesion. At the same time, the fibrin mesh is formed inside the clot. This becomes possible because flow does not penetrate the clot and cannot wash out the reactants participating in blood coagulation. Platelets covered by the fibrin mesh cannot attach new platelets. Modelling shows that the growth of a hemostatic plug can stop as a result of its exterior part being removed by the flow thus exposing its non-adhesive core to the flow.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 337, 21 November 2013, Pages 30-41
نویسندگان
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