کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6382757 1625971 2012 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Slow O-demethylation of methyl triclosan to triclosan, which is rapidly glucuronidated and sulfonated in channel catfish liver and intestine
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم آبزیان
پیش نمایش صفحه اول مقاله
Slow O-demethylation of methyl triclosan to triclosan, which is rapidly glucuronidated and sulfonated in channel catfish liver and intestine
چکیده انگلیسی
► This is the first study of triclosan and methyl triclosan biotransformation in a fish species ► Methyl triclosan was very slowly O-demethylated in the channel catfish liver and intestine ► The demethylation was inhibited by DMSO, a solvent commonly used in toxicology studies ► Triclosan was rapidly conjugated by glucuronidation and sulfonation ► Our results suggest methyl triclosan, but not triclosan, will bioaccumulate in exposed catfish.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Aquatic Toxicology - Volumes 124–125, 15 November 2012, Pages 72-82
نویسندگان
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