کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6450943 1416155 2017 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewCurrent status on clinical applications of magnesium-based orthopaedic implants: A review from clinical translational perspective
ترجمه فارسی عنوان
بررسی وضعیت فعلی در مورد کاربرد های بالینی ایمپلنت های ارتوپدی مبتنی بر منیزیم: بررسی از دیدگاه بالینی ترجمه
کلمات کلیدی
منیزیم، کاربرد ارتوپدی، پزشکی ترجمه فهرست،
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
چکیده انگلیسی

As a new generation of medical metallic material, magnesium (Mg) and its alloys with or without surface coating have attracted a great deal of attention due to its biodegradability and potential for avoiding a removal operation after the implant has fulfilled its function for surgical fixation of injured musculoskeletal tissues. Although a few clinical cases on Mg-based orthopaedic implants were reported more than a century ago, it was not until recently that clinical trials using these implants with improved physicochemical properties were carried out in Germany, China and Korea for bone fracture fixation. The promising results so far suggest a bright future for biodegradable Mg-based orthopaedic implants and would warrant large scale phase II/III studies. Given the increasing interest on this emerging biomaterials and intense effort to improve its properties for various clinical applications, this review covers the evolution, current strategies, and future perspectives in the development of Mg-based orthopaedic implants. We also highlight a few clinical cases performed in China that may be unfamiliar to the general orthopaedic community.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomaterials - Volume 112, January 2017, Pages 287-302
نویسندگان
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