کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6484853 365 2016 42 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mechanisms by which acellular biologic scaffolds promote functional skeletal muscle restoration
ترجمه فارسی عنوان
مکانیسم هایی که توسط داربست های بیولوژیک سلولی ترویج عملکرد عضلات اسکلتی عملکردی را بهبود می بخشد
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
چکیده انگلیسی
Acellular biologic scaffolds derived from extracellular matrix have been investigated in preclinical and clinical studies as a regenerative medicine approach for volumetric muscle loss treatment. The present manuscript provides a review of previous studies supporting the use of extracellular matrix derived biologic scaffolds for the promotion of functional skeletal muscle tissue formation that is contractile and innervated. The manuscript also identifies key mechanisms that have been associated with ECM-mediated skeletal muscle repair, and provides hypotheses as to why there have been variable outcomes, ranging from successful to unsatisfactory, associated with ECM bioscaffold implantation in the skeletal muscle injury microenvironment
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomaterials - Volume 103, October 2016, Pages 128-136
نویسندگان
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