Reaction-dependent heteroatom modification of acid-base catalytic cooperativity in aminosilica materials

- Heteroatom-substituted aminosilica bifunctional silica catalysts prepared.
- Heteroatom substitutions create Lewis acid sites.
- Heteroatom-containing materials have reduced catalytic activity in the aldol condensation.
- Modest amount of Lewis acid sites increases activity for the nitroaldol condensation.