Highly active binuclear Cu(II) catalyst bearing an unsymmetrical bipyridine-pyrazole-amine ligand for the azide-alkyne cycloaddition reaction

Binuclear Cu(II) complex bearing an unsymmetrical bipyridine-pyrazole-amine ligand was synthesized. The complex was an excellent catalyst in the CuAAC reaction. At 0.1-0.3 mol% catalyst loading all the 1,4-disubstituted triazoles were obtained in 95-99% isolated yields.