Two-stage extraction of antitumor, antioxidant and antiacetylcholinesterase compounds from Ganoderma lucidum fruiting body

- Two stage extraction and evaluation of bioactivity of extracts from G. lucidum was performed.
- Anti-AChE activity of G. lucidum SCCO2 extracts was for the first time evaluated.
- Target antiadenocarcinoma activity of G. lucidum SCCO2 extracts was observed.
- Influence of extraction process parameters on biological activity of extracts is discussed.
- G. lucidum as source of strong bioactives for support treatment of Alzheimer's disease is highlighted.