Influence of process variables on granulation of microcrystalline cellulose in vibrofluidized bed

► Microcrystalline cellulose (MCC) was adequately granulated in vibrofluidized bed. ► Vibration parameters and operating conditions influenced process performance. ► Granulation resulted in particle growth from 3.18 to 33.11% considering mean diameter. ► Range of angle of repose classifies granulated MCC as having excellent flowability.