Calorimetric study of adsorption of human serum albumin onto silica powders

Silica materials with different surface functionalities were synthesized by sol–gel method. The isothermal enthalpies of adsorption of human serum albumin (ΔadsHHSA) onto the silica surfaces from buffer solution (pH = 7.4) were measured at 298.15 K. The values of ΔadsHHSA were found to be endothermic. Possible contributions to ΔadsHHSA are discussed.