کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
675376 | 1459606 | 2008 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antibacterial activities of manganese(II) ebselen–porphyrin conjugate and its free components on Staphylococcus aureus investigated by microcalorimetry
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
جریان سیال و فرایندهای انتقال
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Antibacterial activities of manganese(II) ebselen–porphyrin conjugate and its free components on Staphylococcus aureus investigated by microcalorimetry Antibacterial activities of manganese(II) ebselen–porphyrin conjugate and its free components on Staphylococcus aureus investigated by microcalorimetry](/preview/png/675376.png)
چکیده انگلیسی
The antibacterial effect of Mn(II), tetraphenyl porphyrin (TPP), ebselen–porphyrin conjugate 1 and its manganese(II) complex 2 towards Staphylococcus aureus growth was studied by stop-flow microcalorimetry. By analyzing the power–time curves, crucial parameters such as rate constant of bacterial growth (k), half inhibitory concentration (IC50), and generation time (tG) were determined. The sequence of the antibacterial activities of these compounds tested was 2 > 1 > Mn(II) > TPP, with an IC50 value of 100 μg/mL for complex 2. Manganese(II) ebselen–porphyrin conjugate 2 is proposed to benefit from synergetic effects of Mn(II) and 1.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Thermochimica Acta - Volume 476, Issues 1–2, 30 September 2008, Pages 33–38
Journal: Thermochimica Acta - Volume 476, Issues 1–2, 30 September 2008, Pages 33–38
نویسندگان
Xiang-Jiao Xu, Zhi Xue, Zu-De Qi, An-Xin Hou, Chao-Hong Li, Yi Liu,