کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
676153 887759 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Inhibitory study of some novel Schiff base derivatives on Staphylococcus aureus by microcalorimetry
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی جریان سیال و فرایندهای انتقال
پیش نمایش صفحه اول مقاله
Inhibitory study of some novel Schiff base derivatives on Staphylococcus aureus by microcalorimetry
چکیده انگلیسی

The effect of a series of novel Schiff base compounds on Staphylococcus aureus was studied by microcalorimetric method at 37 °C The results showed that all of the organic compounds had the capacity to inhibit the growth of S. aureus in different extent. And the extent and duration of the inhibitory effect on the growth of S. aureus, judged from the rate constant (k), varied with the different structure of the Schiff base compounds. According to the power–time curves, the multiplication rate constant and inhibition ratio were calculated. The growth rate constant of S. aureus (in log phase) in the presence of Schiff base compounds decreased with the increasing of the concentrations of these compounds regularly. The experimental results revealed that the hydrophilicity of Schiff bases had a great influence on their antibacterial activity. Of these Schiff bases, the greater their hydrophilicity, the higher their antibacterial activity. The antibacterial structure–activity relationship (SAR) of Schiff base derivatives was also briefly discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Thermochimica Acta - Volume 440, Issue 1, 1 January 2006, Pages 51–56
نویسندگان
, , , , , ,