کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6888277 1444920 2018 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fiber Bragg grating based temperature profiling in ferromagnetic nanoparticles-enhanced radiofrequency ablation
ترجمه فارسی عنوان
پروفیل درجه حرارت بر اساس فیبر برغرب در نانوذرات فرومغناطیسی - افزایش سرعت رادیوفرکانسی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر شبکه های کامپیوتری و ارتباطات
چکیده انگلیسی
In this work, we report the real-time temperature profiling performed with a fiber Bragg grating (FBG) sensing system, applied to a ferromagnetic nanoparticles (NP)-enhanced radiofrequency ablation (RFA) for interventional cancer care. A minimally invasive RFA setup has been prepared and applied ex vivo on a liver phantom; NPs (with concentrations of 5 and 10 mg/mL) have been synthesized and injected within the tissue prior to ablation, in order to facilitate the heat distribution to the peripheral sides of the treated tissue. A network of 15 FBG sensors has been deployed in situ in order to detect the parenchymal temperature distribution and estimate the thermal profiles in real time during the ablation, highlighting the impact of the NPs on the RFA mechanism. The results confirm that NP-enhanced ablation with 5 mg/mL density shows a better heat penetration that a standard RFA achieving an almost double-sized lesion, while a higher density (10 mg/mL) does not improve the heat distribution. Thermal data are reported highlighting both spatial and temporal gradients, evaluating the capability of NPs to deliver sufficient heating to the peripheral sides of the tumor borders.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Optical Fiber Technology - Volume 43, July 2018, Pages 145-152
نویسندگان
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