کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6930006 | 867666 | 2016 | 19 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Variable viscosity and density biofilm simulations using an immersed boundary method, part II: Experimental validation and the heterogeneous rheology-IBM
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
نرم افزارهای علوم کامپیوتر
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Variable viscosity and density biofilm simulations using an immersed boundary method, part II: Experimental validation and the heterogeneous rheology-IBM Variable viscosity and density biofilm simulations using an immersed boundary method, part II: Experimental validation and the heterogeneous rheology-IBM](/preview/png/6930006.png)
چکیده انگلیسی
We validate our modeling approach from Part I by comparing dynamic moduli and compliance moduli computed from our model to data from mechanical characterization experiments on Staphylococcus epidermidis biofilms. The experimental setup is described in [26] in which biofilms are grown and tested in a parallel plate rheometer. In order to initialize the positions of bacteria in the biofilm, experimentally obtained three dimensional coordinate data was used. One of the major conclusions of this effort is that treating the spring-like connections between bacteria as Maxwell or Zener elements provides good agreement with the mechanical characterization data. We also found that initializing the simulations with different coordinate data sets only led to small changes in the mechanical characterization results. Matlab code used to produce results in this paper will be available at https://github.com/MathBioCU/BiofilmSim.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Computational Physics - Volume 317, 15 July 2016, Pages 204-222
Journal: Journal of Computational Physics - Volume 317, 15 July 2016, Pages 204-222
نویسندگان
Jay A. Stotsky, Jason F. Hammond, Leonid Pavlovsky, Elizabeth J. Stewart, John G. Younger, Michael J. Solomon, David M. Bortz,