Reliability analysis of an integrated device of ECG, PPG and pressure pulse wave for cardiovascular disease

Cardiovascular diseases (CVD) are the leading cause of death globally and the mortality has been increasing in recent two decades. Most of cardiovascular diseases are preventable by early and long-term monitoring. The common option of physical examinations for CVD includes ECG, photoplethysmography (PPG), pressure pulse wave (PPW). An integrated device was designed and developed by gathering three physiological signals of ECG, PPG, and PPW synchronusly in this research. The tri-modal device was tested for reliability and stability on the synchronism of R-R intervals, distribution of peaks, and noise suppression. The experiment results displayed that the white noise and dark noise was well controlled. In the test of synchronism, PPG and PPW of the P-P intervals show a good linearity in correspondence with the ECG of R-R intervals in cardiac cycle. There is no significant difference in peak distribution of three modal signals from 4 volunteers. Thus, the equipment has excellent properties of anti-electromagnetic interference, removing movement artifacts and light tightness and may be developed to a promising tool for multi-modal diagnosis in CVD.