Comparison of driving simulator performance with real driving after alcohol intake: A randomised, single blind, placebo-controlled, cross-over trial

► This validation study compared simulated and real driving after ethanol intake. ► 20 subjects underwent three 1 h trips each in a simulator and on a test track. ► Blood alcohol concentration and car weaving (SDLP) were significantly correlated. ► SDLP values were higher and showed greater variance in the simulator. ► The simulator is a sensitive and valid tool to detect ethanol impaired driving.