Investigation on the Human Hepatoma HEPG2 Cells Adhesion under the Synergy of Stiffness and Superhydrophobicity

Synergy of stiffness and superhydrophobicity is used to regulate liver cancer cells adhesion on the PDMS substrates. The adhering and spreading behaviors of HEPG2 cells are confined on the soft superhydrophobic substrate compared to stiff one. Moreover the cancer cells morphology of spreading and spherical conformations can be controlled on the designed stiffness-soft surface412