کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7126047 1461540 2014 21 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Rapid and simultaneous determination of tetracycline and cefixime antibiotics by mean of gold nanoparticles-screen printed gold electrode and chemometrics tools
ترجمه فارسی عنوان
تعیین سریع و همزمان آنتی بیوتیک های تتراسایکلین و سفلیسیم با استفاده از ابزارهای الکترودهای طلای الکترود طلا و نانوذرات طلا
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی کنترل و سیستم های مهندسی
چکیده انگلیسی
The screen-printed gold electrode (SPGE) modified with the formation of self-assembly monolayer (SAM) of cysteine (Cys) on gold-nanoparticles (Aunano) was utilized for rapid and simultaneous determination of tetracycline and cefixime antibiotics by square wave voltammetry (SWV). Electrochemical investigation and characterization of the modified electrode was achieved using cyclic voltammetry (CV) and scanning electron microscopy (SEM). A principal component artificial neural network (PCANN) with three layer back-propagation network was utilized for the analysis of the voltammogram data. It is possible to simultaneously determine the tetracycline and cefixime concentrations in the ranges of 10−5 and 10−3 mol L−1, under the optimum conditions. Moreover the SPGE-Aunano-Cys biosensor together with chemometrics tools was successfully applied to the determination of tetracycline and cefixime in biological fluids, which may provide a promising alternative in routine biosensing applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Measurement - Volume 47, January 2014, Pages 145-149
نویسندگان
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