کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7138714 1462015 2018 32 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A core-shell MWCNT@rGONR heterostructure modified glassy carbon electrode for ultrasensitive electrochemical detection of glutathione
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
A core-shell MWCNT@rGONR heterostructure modified glassy carbon electrode for ultrasensitive electrochemical detection of glutathione
چکیده انگلیسی
In this work, a multiwalled carbon nanotubes@reduced graphene oxide nanoribbons core-shell heterostructure (MWCNT@rGONR)-modified glassy carbon electrode (MWCNT@rGONR/GCE) was employed to electrochemically detect glutathione (GSH). The morphologies and microstructures of the as-prepared MWCNT@rGONR heterostructure were examined by field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy spectrum (FT-IR), respectively. The electrochemical characteristics and catalytic behaviors of the fabricated sensor for determination of GSH were systematically investigated by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), differential pulse voltammetry (DPV), and amperometry (i-t). Under optimum conditions, the MWCNT@rGONR heterostructure modified electrode possesses the ability of strong electrocatalytic for GSH with high selectivity and sensitivity, fast response, wide linear range, low detection limit (39 nM) and outstanding reproducibility. Its further application for the quantification of GSH concentration in human serum samples was also demonstrated with satisfactory accuracy. These features indicate that the prepared core-shell MWCNT@rGONR heterostructure with unique electronic structure offers an excellent biosensing platform for sensitive and selective detection of glutathione.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 274, 20 November 2018, Pages 433-440
نویسندگان
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