Caspase-1 assay based on peptide and luminol labeled gold nanoparticle as chemiluminescence probe coupling magnetic separation technology

A chemiluminescence biosensor for detection of caspase-1 was developed by using peptide cleavage technology with LOD 0.003 ng mL−1. Peptide and luminol labeled gold nanoparticles were used as a chemiluminescence probe and magnetic beads was used as immobilization matrix.