Electrochemical sensing platform based on Pd-Au bimetallic cluster for non-enzymatic detection of glucose

Bimetallic Pd-Au cluster was synthesized through a direct chemical reduction method and utilized for the fabrication of electrochemical sensing platform. Scanning electron microscopy (SEM) characterization indicated the obtained Pd-Au cluster displays branch-type structure that composed of nanowires. As a demonstration of the application of the sensing platform, the performance of the platform toward non-enzymatic electrochemical detection of glucose was studied. Analytical results show improved activity of the Pd-Au cluster toward glucose oxidation with high sensitivity, wide linear range and good stability. When the electrode was used for the detection of glucose in blood samples, the glucose contents detected by the electrode was in good agreement with those from the hospital. The proposed electrochemical sensing platform can certainly be expanded to the fabrication of other kinds of electrochemical sensors and biosensors.