A ratiometric colorimetric and fluorescent chemosensor for rapid detection hydrogen sulfide and its bioimaging

A colorimetric and fluorescent chemosensor bearing hybrid coumarin-hemicyanine functionality has been synthesized for H2S sensing. The detection of sulfide was performed via the nucleophilic attack toward the polarized CN and an electron-poor CC bond of the probe, which can provide a potentially powerful approach for probing H2S chemistry in biological system.