Molecular modeling of the elastomeric properties of repeating units and building blocks of resilin, a disordered elastic protein

- MD simulations were used to characterize stiffness of amino acid sequences.
- Repetitive motif sequence and order of amino acid strongly influence chain stiffness.
- Certain repeat motifs favor bent structure conformations with low stiffness.
- Intramolecular hydrogen bonds may help maintain bent conformation.
- The amino acid sequence corresponding to resilin has very low stiffness.