کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7208082 1469086 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fabrication of an integrated cartilage/bone joint prosthesis and its potential application in joint replacement
ترجمه فارسی عنوان
ساخت یک پروتز متحرک غضروف / استخوان و کاربرد بالقوه آن در جایگزینی مفصل
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
چکیده انگلیسی
An integrated cartilage/bone joint prosthesis was designed and fabricated using a two-step molding injection method, in which ethylene-vinyl acetate copolymer (EVA) was used as the upper cartilage layer, and hydroxyapatite/polyamide66 (HA/PA66) composites as the underlying bone layer. Holes punched in the underlying layer improved the interfacial bonding strength between the two layers by means of the mechanical interlocking obviously. Then, the physicochemical properties and in vivo behaviors of the integrated joint prosthesis were investigated. The results showed that the upper layer displayed good bio-tribological properties which were suitable for the articular cartilage replacement, while the underlying layer demonstrated good mechanical performance, excellent biocompatibility and high bioactivity, and could accelerate bone regeneration and the early bio-fixation of the prosthesis. Therefore, the prosthesis prepared here will have a wide prospect to be used in joint replacement.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 59, June 2016, Pages 265-271
نویسندگان
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