کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7208406 1469095 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Fabrication and characterization of novel microneedles made of a polystyrene solution
ترجمه فارسی عنوان
ساخت و مشخص نمودن میکروسکوپ های جدید ساخته شده از محلول پلی استایرن
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
چکیده انگلیسی
Nowadays, microneedles are attracting a lot of attention because microneedles can deliver drugs, vaccines and hormones into the body without pain unlike conventional hypodermic needles. Furthermore, microneedles are safe for self-injection and disposal. This work aims to develop novel microneedles made of a solution of polystyrene (PS) in toluene. The mechanical properties of the fabricated PS microneedles were characterized in failure strength test and skin penetration test. According to the experimental results, a PS microneedle could withstand a large force up to 1.0 N without fracturing. Owing to the superior mechanical strength, the PS microneedles could penetrate the skin without any deterioration making them a promising alternative for commercial applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Mechanical Behavior of Biomedical Materials - Volume 50, October 2015, Pages 77-81
نویسندگان
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