کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7215952 | 1469540 | 2013 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Halloysite nanotube nanocomposite hydrogels with tunable mechanical properties and drug release behavior
ترجمه فارسی عنوان
هیدروژل نانوکامپوزیت هالوویستی با خواص مکانیکی قابل تنظیم و رفتار انتشار مواد مخدر
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موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی (عمومی)
چکیده انگلیسی
Nanocomposite hydrogels with tunable mechanical properties and drug release behavior were prepared by halloysite nanotube (HNT), oligo(trimethylene carbonate)-poly(ethylene glycol)-oligo(trimethylene carbonate) diacrylate (TPT), and alginate sodium (AG). The mechanical properties of the hydrogel were greatly enhanced by the addition of small amount of HNT (2Â wt%). The drug release behavior of the hydrogels was examined using bovine serum albumin (BSA) as model drug, and TPT hydrogel showed a fickcian diffusion controlled release mechanism, while the BSA transport mechanism in TPT-HNT, TPT-AG, and TPT-AG-HNT hydrogels were anomalous transport. The cytocompatibility of the hydrogel were verified by the MTT assay, and the hydrogel showed comparable cytocompatibility with the widely recognized poly(ethylene glycol) hydrogel.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Composites Science and Technology - Volume 85, 21 August 2013, Pages 126-130
Journal: Composites Science and Technology - Volume 85, 21 August 2013, Pages 126-130
نویسندگان
Jiaxing Tu, Zheng Cao, Yihan Jing, Changjiang Fan, Chao Zhang, Liqiong Liao, Lijian Liu,