Investigation of nonlinear optical behavior of creatinine for measuring its concentration in blood plasma

Since creatinine reflects the Kidneys function in the human body, the accurate measuring methods to assess the concentration of creatinine in blood plasma are important. Colorimetric method is usually used to measure the concentration of creatinine in blood plasma. In this paper, we have applied Z-scan technique to investigate the nonlinear behavior of creatinine of blood plasma. The samples include different concentrations of creatinine. The concentration of creatinine directly changes the nonlinear refractive index of samples. As a result, this method can be used to measure the creatinine concentration of blood plasma.