کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7235980 1471090 2018 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessment of human left ventricle flow using statistical shape modelling and computational fluid dynamics
ترجمه فارسی عنوان
بررسی جریان بطن چپ انسانی با استفاده از مدل آماری شکل و دینامیک سیالات محاسباتی
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
چکیده انگلیسی
Blood flow patterns in the human left ventricle (LV) have shown relation to cardiac health. However, most studies in the literature are limited to a few patients and results are hard to generalize. This study aims to provide a new framework to generate more generalized insights into LV blood flow as a function of changes in anatomy and wall motion. In this framework, we studied the four-dimensional blood flow in LV via computational fluid dynamics (CFD) in conjunction with a statistical shape model (SSM), built from segmented LV shapes of 150 subjects. We validated results in an in-vitro dynamic phantom via time-resolved optical particle image velocimetry (PIV) measurements. This combination of CFD and the SSM may be useful for systematically assessing blood flow patterns in the LV as a function of varying anatomy and has the potential to provide valuable data for diagnosis of LV functionality.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 74, 6 June 2018, Pages 116-125
نویسندگان
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