کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
724057 892361 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
NORMALISATION OF DNA ARRAY DATA TO FACILITATE THEIR USE IN BIOPROCESS DEVELOPMENT
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مکانیک محاسباتی
پیش نمایش صفحه اول مقاله
NORMALISATION OF DNA ARRAY DATA TO FACILITATE THEIR USE IN BIOPROCESS DEVELOPMENT
چکیده انگلیسی

The application of DNA array is spreading at a very fast rate, although mainly in medical and systems biology studies. However, the recent FDA Process Analytical Technologies initiative provides a very exciting possibility of using transcriptomics, proteomics and metabolomics to gain deeper bioprocess understanding leading to more rapid process development and tighter control of critical process parameters. This contribution introduces a method of normalisation necessary for DNA data analysis usable in such circumstances – i.e. a limited number of experiments under varying operational conditions. We show that this normalisation technique provides more plausible data preparation for further data analysis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: IFAC Proceedings Volumes - Volume 40, Issue 4, 2007, Pages 55–60
نویسندگان
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