کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7283946 | 1474030 | 2015 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Structural alterations of the language connectome in children with specific language impairment
ترجمه فارسی عنوان
تغییرات ساختاری زبان در کودکان مبتلا به اختلال زبان خاص در ارتباط است
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
چکیده انگلیسی
We evaluated brain white matter pathways associated with language processing in 37 children with specific language impairment aged 6-12Â years and 34 controls, matched for age, sex and handedness. Arcuate fascicle (AF), inferior fronto-occipital fascicle (IFOF), inferior longitudinal fascicle (ILF) and uncinate fascicle (UF) were identified using magnetic resonance diffusion tensor imaging (DTI). Diffusivity parameters and volume of the tracts were compared between the SLI and control group. Children with SLI showed decreased fractional anisotropy in all investigated tracts, increased mean diffusivity and radial diffusivity component in arcuate fascicle bilaterally, left IFOF and left ILF. Further, bilaterally increased volume of the ILF in children with SLI was found. We confirmed previous findings indicating deficient connectivity of the arcuate fascicle and as a novel finding, demonstrate abnormal development of the ventral language stream in patients with SLI.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Language - Volume 151, December 2015, Pages 35-41
Journal: Brain and Language - Volume 151, December 2015, Pages 35-41
نویسندگان
Rosa Vydrova, Vladimir Komarek, Jan Sanda, Katalin Sterbova, Alena Jahodova, Alice Maulisova, Jitka Zackova, Jindra Reissigova, Pavel Krsek, Martin Kyncl,