کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7288347 | 1474167 | 2016 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Catechol-O-methyltransferase (COMT) gene modulates private self-consciousness and self-flexibility
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Catechol-O-methyltransferase (COMT) gene modulates private self-consciousness and self-flexibility Catechol-O-methyltransferase (COMT) gene modulates private self-consciousness and self-flexibility](/preview/png/7288347.png)
چکیده انگلیسی
Dopamine levels in the brain influence human consciousness. Inspired by the role of Catechol-O-methyltransferase (COMT) in inactivating dopamine in the brain, we investigated to what extent COMT could modulate individual's self-consciousness dispositions and self-consistency by genotyping the COMT Val158Met (rs4680) polymorphism and measuring self-consciousness and self-consistency and congruence in a college student population. The results indicated that COMT Val158Met polymorphism significantly modulated the private self-consciousness. The individuals with Val/Val genotype, corresponding to lower dopamine levels in the brain, were more likely to be aware of their feelings and beliefs. The results also indicated that this polymorphism modulated one's self-flexibility. The individuals with Val/Val genotype showed higher levels of stereotype in self-concept compared with those with Met/Met genotype. These findings suggest that COMT is a predictor of the individual differences in self-consciousness and self-flexibility.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Consciousness and Cognition - Volume 44, August 2016, Pages 186-192
Journal: Consciousness and Cognition - Volume 44, August 2016, Pages 186-192
نویسندگان
Bei Wang, Wenzhao Ru, Xing Yang, Lu Yang, Pengpeng Fang, Xu Zhu, Guomin Shen, Xiaocai Gao, Pingyuan Gong,