کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
731292 893047 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Uncertainty evaluation for determining linezolid in injectable solution by UV spectrophotometry
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی کنترل و سیستم های مهندسی
پیش نمایش صفحه اول مقاله
Uncertainty evaluation for determining linezolid in injectable solution by UV spectrophotometry
چکیده انگلیسی


• We identify several sources of uncertainty in quantification of linezolid.
• We evaluate how each uncertainty source contributes to total uncertainty.
• We establish a procedure to calculate combined and expended uncertainties.

The aim of this work was to identify the main sources of uncertainty, quantify the standard deviation of each source of uncertainty, and calculated combined and expended uncertainties for the determination of linezolid in injectable dosage forms by UV spectrophotometry. The contributions of precision, linearity and weight of linezolid reference standard are the most significant, contributing with about 77% of the overall uncertainty. The uncertainties on the absorbances (sample and standard), volumetric flasks and volumetric pipettes have virtually no influence on the overall uncertainty. The estimated uncertainty of the spectrophotometric method for determination of linezolid was adequate for the scope of the method.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Measurement - Volume 46, Issue 10, December 2013, Pages 3924–3928
نویسندگان
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